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The 10th Naito Conference

Molecular Biological Approaches for Intractable Diseases [I]

Period 1998/10/29 (Thu.) - 1998/11/01 (Sun.)
Venue Naito Museum of Pharmaceutical Science and Industr(Kakamigahara-shi, Gifu-pref)
Participants Lectures:25
Posters:60

Committee

Ichiro Kanazawa The University of Tokyo
Nobuhiro Yamada The University of Tokyo
Susumu Seino Chiba University
Gen Sobue Nagoya University
Tsuneyo Mimori Keio University

Session

SessionA
Molecular Genetics of Diabetes Mellitus

  1. Molecular Approach for Insulin Secretion Defects in Diabetes Mellitus
    [Yoshitomo Oka]
    Yamaguchi University School of Medicine, Japan
  2. Amylin Gene: Gene Susceptibility to Early Onset of Japanese Type 2 Diabetes
    [Tokio Sanke]
    Wakayama University of Medical Science, Japan
  3. Molecular Structure of Pancreatic Islets
    [Jun Takeda]
    Gunma University, Institute for Molecular and Cellular Regulation, Japan
  4. From Genomics to Aetiology in the Multifactorial Disease Type 1 Diabetes
    [John A. Todd]
    Cambridge Institute for Medical Reseaerch, University of Cambridge, UK
  5. Molecular Genetics of Non-Insulin Dependent Diabetes Mellitus
    [Graeme I. Bell]
    Howard Hughes Medical Institute, The University of Chicago, USA

SessionB
Molecular Genetics of Metabolic Disease: Lessons from Animal Models

  1. Watanabe Heritable Hyperlipidemic Rabbits and the LDL Receptor Gene Family
    [Tokuo T. Yamamoto]
    Tohoku University, Gene Research Center, Japan
  2. Genetic Analysis of Spontaneously Hypertensive Rats (SHR), An Animal Model of Hypertension and Insulin Resistance
    [Takanari Gotoda]
    University of Tokyo, Japan
  3. Genetics of Diabetes and its Associated Phenotypes in the GK Rat
    [Holger Luthman]
    Karolinska Institute, Sweden
  4. Role of the POMC Neurons in the Regulation of Feeding and Metabolism
    [Roger D. Cone]
    Vollum Institute, Oregon Health Sciences University, USA
  5. Genetic Causes of Obesity in Childhood
    [Stephen O'rahilly]
    University of Cambridge, Addenbrook's Hospital, UK

SessionC
Molecular Biology of Metabolic Disease

  1. Lipoprotein Metabolism and its Molecular Abnormalities
    [Yokode Masayuki]
    Kyoto University Granduate School of Medicine, Japan
  2. Downstream Effectors of PI 3-Kinase in Insulin Action
    [Masato Kasuga]
    Kobe University School of Medicine, Japan
  3. The KATP Channel in Pancreatic β-Cells: The ATP and ADP Sensor in Insulin Secretion
    [Susumu Seino]
    Chiba University, Graduate School of Medicine, Japan
  4. Molecular Basis of Beta-Cell Destruction and IDDM
    [Jorn Nerup]
    Steno Diabetes Center, Denmark
  5. Exploring the Role of the Mitochondrial Uncoupling Proteins and Brown Adipocytes in tbe Regulation of Body Weight
    [Leslie P. Kozak]
    The Pennington Biomedical Research Center, USA

SessionD
Apotosis in Intractable Diseases

  1. Fas-Mediated Apoptosis and Disease
    [Shigekazu Nagata]
    Osaka University Medical School, Japan
  2. Roles of Fas Ligand and TNF α in Chronic Inflammatory Disease; Prospect for Gene Therapy
    [John D. Mountz]
    The University of Alabama at Birmingham, USA
  3. Mechanisms of Pancreatic β Cell Death in Diabetes
    [Daniel Pipeleers]
    Diabetes Research Center, Vrije Universiteit, Belgium
  4. Polyglutamine Disease and Apoptosis
    [Akira Kakizuka]
    Osaka Biocience Institute, Japan
  5. Insights into the Molecular Basis of Huntington's Disease and Other Polyglutamine Disorders
    [Gillian P. Bates]
    UMDS, Guy's Hospital, University College London, UK

SessionE
Protein Modification and Intractable Diseases

  1. Defects of Signal Transduction via TCR-CD3 Complex in Patients with Systemic Lupus Eryhtematosus - Altered Expression of TCR Zeta Chain
    [Tsutomu Takeuchi]
    Saitama Medical Center, Saitama Medical School, Japan
  2. RAGE: Involvement in the Pathogenesis of Diabetic Complications and Cellular Dysfunction in Amyloidoses
    [David M. Stern]
    College of Physicians and Surgeons of Columbia University, USA
  3. Carbonyl Stress and Metabilic and Neurological Diseases
    [Toshio Miyata]
    Tokai University School of Medicine, Japan
  4. Intracytoplasmic Inclusions and Mechanisms of Neurodegenerative Disease
    [James E. Galvin]
    Allegheny University of the Health Scinences, USA
  5. CAG Repeat Diseases - similarities and dissimilarities with the other 'protein storage disorder's
    [Nobuyuki Nukina]
    RIKEN Brain Science Institute, Japan