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The 16th Naito Conference

Innate Immunity in Medicine and Biology [I]

Period 2003/10/28 (Tue.) - 2003/10/31 (Fri.)
Venue Shonan Village Center( Kanagawa-pref.)
Participants Lectures:25


Shizuo Akira Osaka University
Kayo Inaba Kyoto University
Kensuke Miyake The University of Tokyo



  1. Pattern Recognition Proteins and the Insect Prophenoloxidase Cascade that Possibly be Involved in the Extracellular signaling for the Induction of Immune Protein Synthesis
    [Masaaki Ashida]
    Institute of Low Temperature Science, Hokkaido University, Japan
  2. Recognition and Signaling in Drosophila Immunity
    [Dan Hultmark]
    Umea Center for Molecular Pathogenesis, Umea University, Sweden
  3. Macrophage Activation in Innate Immune Responses: From Genes to Function
    [Alan Aderem]
    Institute for System Biology, USA
  4. Innate Recognition of Lipopolysaccharide by Toll-like Receptor 4 (TLR4)-MD-2
    [Kensuke Miyake]
    Division of Infectious Genetics, The Institute of Medical Science, The University of Tokyo, Japan
  5. Functional Role of Adaptors in the Toll-like Receptor Signaling
    [Shizuo Akira]
    Department of Host Defence, Research Institute for Micdobial Disease, Osaka University, Japan


  1. Mannose-Binding Lectin in Host Defense
    [Kazue Takahashi]
    Laboratory of Developmental Immunology, Massachusetts General Hospital, Harvard Medical School, USA
  2. Role of Mannan-Binding Protein, MBP, in Innate Immunity
    [Toshisuke Kawasaki]
    Department of Biological Chemistry, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan
  3. Mouse C-type Lectins in Antigen Capture and Presentation
    [Kayo Inaba]
    Laboratory of Immunobiology, Department of Animal Development and Physiology, Division of Systemic Life Science, Graduate School of Biostudies, Kyoto University, Japan
  4. DC-Lectin Recognition of Self and Non-Self
    [Yvette van Kooyk]
    Department of Molecular Cell Biology, Vumc, The Netherlands
  5. Molecular Evolution of Mannose-Binding Lectin(MBL), Ficolin, and MBL-Associated Serine Protease (MASP)
    [Teizo Fujita]
    Department of Biochemistry, Fukushima Medical University, Japan

Phagocytosis and Digestion

  1. Mechanisms and Consequences of Phagocytosis in Innate Immunity
    [Peter M. Henson]
    National Jewish Medical Research Center, USA
  2. Negative Regulation of Macrophage Function through CD47 / SIRPα Interaction
    [Per-Arne Oldenborg]
    Department of Integrative Medical Biology, Umea University, Sweden
  3. Molecular Mechanism and Physiological Functions of Autophagy
    [Yoshinori Osumi]
    Department of Cell Biology, Okazaki National Institute for Basic Biology, Jpana
  4. Dependency on MHC Allelic Polymotphism in PA28-Regulated Antigen Processing
    [Heiichiro Udono]
    Department of Molecular Medicine, Division of Immunology, Nagasaki University School of Medicine, Japan
  5. DNA Degradation and its Failure in Programmed Cell Death and Other Developmental Processes
    [Shigekazu Nagata]
    Department of Genetics, Osaka Univesity Medical School, and Laboratory of Genetics, Integrated Biology Laboratories, Graduate School of Frontier Biosciences, Osaka University, Japan

Signaling and Effector

  1. The Nox Family of NADPH-Oxidases: At the Crosroads of Cancer and Innate Immunity
    [J. David Lambeth]
    Department of Pathology and Laboratory Medicine, Emory University Medical School, USA
  2. Reactive Oxygen Species as Microbicidal Agents: Molecular Mechanism for Activation of the Superoxide-Producing Phagocyte NADPH Oxidase
    [Hideki Sumimoto]
    Medical Institute of Bioregulation, Kyushu University, Japan
  3. The Unfolded Protein Response: Signaling from the Endoplasmic Reticulum to the Nucleus
    [Kazutoshi Mori]
    Graduate School of Biosdudies, Kyoto University, Japan
  4. Anti-Microbial Peptides as Signaling and Effector Molecules of Innate Immunity
    [Richard L. Gallo]
    Division of Dermatology, Department of Medicine and Pediatrics, University of California San Diego, USA
  5. Orchestration of Myeloid and Plasmacytoid Dendritic cells (DCs) in Inducing Cytotoxic T Lymphocytes Through Distinct in Vivo Trafficking Pathway
    [Kouji Matsushima]
    Department of Molecular Preventive Medicine & SORST, Graduate School of Medicine, The University of Tokyo, Japan

Host Defense in Invertebrates

  1. Drosophila Immunity: From Gene Expression Profiles to Molecular Functions
    [Bruno Lemaitre]
    Center de Genetique Molequlaire; CNRS, France
  2. Recognition of Infectious Non-Self and Activation of Immune Responses by Peptidoglycan Recognition Protein (PGRP) -Family Members in Drosophila
    [Shoichiro Kurata]
    Graduate School of Pharmaceutical Sciences, Tohoku University, France
  3. Biochemical Characterization and Biological Functions of Innate Immune Related Proteins During Pro-PO Activation Reaction
    [Lee Bok Luel]
    College of Pharmacy, Pusan National University, Korea
  4. A Serine Protease Zymogen on Horseshoe Crab Hemocyte Functions as a Pattern-Recognition Protein for Lipopolysaccharides
    [Shun-ichiro Kawabata]
    Department of Biology, Faculty of Sciences, Kyushu University, Japan
  5. Innate Immunity in Crustaceans, the Propo-System and Hematopoeisis
    [Kenneth Soderhall]
    Department of Comparative Physiology, Uppsala University, Sweden