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The Naito Conference
The Naito Foundation
The Naito Conference for the fiscal year 2021 is cancelled due to COVID-19. The new schedule will be informed once it is decided.

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The 22nd Naito Conference

Chemical Biology [I] -An Emerging Field Inspired by Natural Product Chemistry-

Period 2008/09/09 (Tue.) - 2008/09/12 (Fri.)
Venue CHATERAISE Gateaux Kingdom SAPPORO(Hokkaido)
Participants Lectures:24


Minoru Isobe Institute of Advanced Research
Hiroyuki Osada Chemical Biology Department
Michio Murata Department of Chemistry
Minoru Ueda Department of Chemistry
Motonari Uesugi Institute for Chemical Research and Institute for Integrated Cell-Material Science


Key Natural Products 1

  1. Lessons from Studying β- and γ- Peptides
    [Dieter Seebach]
    Laboratorium fur Organische Chemie, Departement fur Chemie undo Angewandte Biowissenschaften, ETH-Zurich, Switzerland
  2. Chemical Biology of Plant Movements Using Bioactive Natural Products
    [Minoru Ueda]
    Department of Chemistry, Tohoku University, Japan
  3. Quorum Sensing Pheromone, ComX
    [Youji Sakagami]
    Graduate School of Bioagricultural Sciences, Nagoya University, Japan
  4. Timer Protein in Diapause Eggs of the Silkworm Bombyx mori Changes its Conformation for Time Measurement
    [Minoru Isobe]
    Institute of Advanced Research, Nagoya University / National Tsing Hua University, Taiwan, Japan

Key Natural Products 2

  1. Diverse Chemical Structures and Bioactivities of Marine Natural Products
    [Daisuke Uemura]
    Department of Biosciences and Infomatics, Faculty of Science and Technology, Keio University, Japan
  2. Herbivore-Induced Volatiles in Plant Defense: Early and late events in Enemy-recognition and response
    [Whilhelm Boland]
    Department of Bioorganic Chemistry, Max Planck Institute for Chemical Ecology, Germany
  3. The Ecology, Chemistry, and Evolution of Insect-Bacteria Mutualisms
    [Jon Clardy]
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Japan
  4. Identification of Bioactive peptides and Proteins that Stimulate the Vomeronasal Pheromone Sensory Pathway for Socio-sexual Communication in Mice
    [Kazushige Touhara]
    Department of Integrated Biosciences, The University of Tokyo, Japan
  5. Molecular Mechanisms of Self-incompatibility of Plants
    [Akira Isogai]
    Graduate School of Biological Sciences, Nara Institute of Science and Technology, Japan

Bioanalytical Chemistry

  1. Capturing the Value of Ultra-High Resolution Tandem Mass Spectrometry in Contemporary Chemical Biology
    [Neil L. Kelleher]
    Department of Chemistry University of Illinois, USA
  2. Analyzing Drug Binding Sites in Functionally Competent Membrane Receptors at Sub-Å Resolution
    [Anthony Watts]
    Biomembrane Structure Unit, Biochemistry Department, Oxford University, UK
  3. NMR Approach for Interaction Analysis of Larger Proteins
    [Ichio Shimada]
    Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan
  4. Molecular Assemblies in Biomembrances as Viewed by Solid State NMR
    [Michio Murata]
    Department of Chemistry, Graduate School of Science, Osaka University, Japan
  5. Color Control Mechanism of Firefly Glowing: Crystal Structure and Mechanism of Luminescent Enzyme Luciferase
    [Hiroaki Kato]
    Department of Structural Biology, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan

Small-Molecule-Initiated Biology

  1. Design, Synthesis and Application of Bio-imaging Probes which Convert Biological Signals to Chemical Output
    [Kazuya Kikuchi]
    Graduate School of Engineering, Osaka University, Japan
  2. New Method for Protein Selective Labeling
    [Itaru Hamachi]
    Department of Synthetic Chemistry and Biological Chemistry, Kyoto University, Japan
  3. Defining the Druggable Cysteinome
    [Jack Taunton]
    University of California, San Francisco, USA
  4. Isolating and Identifying the Targets of Bioactive Small Molecules
    [Motonari Uesugi]
    Institute for Chemical Research and Institute for Integrated Cell-Material Science, Kyoto University, Japan
  5. A Small Molecule Approach to Cell Biology
    [Craig M. Crews]
    Departments of Molecular, Cell, and Developmental Biology, Chemistry, and Pharmacology, Yale University, Japan

Target Proteins

  1. Natural Products as Probes of Eukaryotic Translation
    [Jun O. Liu]
    Departments of Pharmacology and Oncology, Johns Hopkins School of Medicine, USA
  2. From Marine Natural Products to Target Proteins: Integrative Approaches in Chemical Biology
    [Hendrik Luesch]
    Department of Medical Chemistry, University of Florida, USA
  3. Glyoxalase 1, a Target Molecule of Methyl-Gerfelin which is an Inhibitor of Osteoclastgenesis
    [Hiroyuki Osada]
    Chemical Biology Department, Advanced Science Institute, RIKEN, Japan
  4. Mapping Dysregulated Biochemical Pathways in Human Disease by Activity-Based Proteomics and Metabolomics
    [Benjamin F. Cravatt]
    Department of Chemical Physiology, The Scripps Research Institute, USA
  5. A New PI3 Kinase Inhibitor ZSTK 474 identified by JFCR39 Cancer Cell Panel
    [Takao Yamori]
    Division of Molecular Pharmacology, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research, Japan