第10回 内藤コンファレンス

難病の分子生物学 [I]

組織委員

セッション

SessionA
Molecular Genetics of Diabetes Mellitus

1. Molecular Approach for Insulin Secretion Defects in Diabetes Mellitus

   [Yoshitomo Oka]

   Yamaguchi University School of Medicine, Japan

2. Amylin Gene: Gene Susceptibility to Early Onset of Japanese Type 2 Diabetes

   [Tokio Sanke]

   Wakayama University of Medical Science, Japan

3. Molecular Structure of Pancreatic Islets

   [Jun Takeda]

   Gunma University, Institute for Molecular and Cellular Regulation, Japan

4. From Genomics to Aetiology in the Multifactorial Disease Type 1 Diabetes

   [John A. Todd]

   Cambridge Institute for Medical Reseaerch, University of Cambridge, UK

5. Molecular Genetics of Non-Insulin Dependent Diabetes Mellitus

   [Graeme I. Bell]

   Howard Hughes Medical Institute, The University of Chicago, USA

SessionB
Molecular Genetics of Metabolic Disease: Lessons from Animal Models

1. Watanabe Heritable Hyperlipidemic Rabbits and the LDL Receptor Gene Family

   [Tokuo T. Yamamoto]

   Tohoku University, Gene Research Center, Japan

2. Genetic Analysis of Spontaneously Hypertensive Rats (SHR), An Animal Model of Hypertension and Insulin Resistance

   [Takanari Gotoda]

   University of Tokyo, Japan

3. Genetics of Diabetes and its Associated Phenotypes in the GK Rat

   [Holger Luthman]

   Karolinska Institute, Sweden

4. Role of the POMC Neurons in the Regulation of Feeding and Metabolism

   [Roger D. Cone]

   Vollum Institute, Oregon Health Sciences University, USA

5. Genetic Causes of Obesity in Childhood

   [Stephen O'rahilly]

   University of Cambridge, Addenbrook's Hospital, UK

SessionC
Molecular Biology of Metabolic Disease

1. Lipoprotein Metabolism and its Molecular Abnormalities

   [Yokode Masayuki]

   Kyoto University Granduate School of Medicine, Japan

2. Downstream Effectors of PI 3-Kinase in Insulin Action

   [Masato Kasuga]

   Kobe University School of Medicine, Japan

3. The KATP Channel in Pancreatic β-Cells: The ATP and ADP Sensor in Insulin Secretion

   [Susumu Seino]

   Chiba University, Graduate School of Medicine, Japan

4. Molecular Basis of Beta-Cell Destruction and IDDM

   [Jorn Nerup]

   Steno Diabetes Center, Denmark

5. Exploring the Role of the Mitochondrial Uncoupling Proteins and Brown Adipocytes in tbe Regulation of Body Weight

   [Leslie P. Kozak]

   The Pennington Biomedical Research Center, USA

SessionD
Apotosis in Intractable Diseases

1. Fas-Mediated Apoptosis and Disease

   [Shigekazu Nagata]

   Osaka University Medical School, Japan

2. Roles of Fas Ligand and TNF α in Chronic Inflammatory Disease; Prospect for Gene Therapy

   [John D. Mountz]

   The University of Alabama at Birmingham, USA

3. Mechanisms of Pancreatic β Cell Death in Diabetes

   [Daniel Pipeleers]

   Diabetes Research Center, Vrije Universiteit, Belgium

4. Polyglutamine Disease and Apoptosis

   [Akira Kakizuka]

   Osaka Biocience Institute, Japan

5. Insights into the Molecular Basis of Huntington's Disease and Other Polyglutamine Disorders

   [Gillian P. Bates]

   UMDS, Guy's Hospital, University College London, UK

SessionE
Protein Modification and Intractable Diseases

1. Defects of Signal Transduction via TCR-CD3 Complex in Patients with Systemic Lupus Eryhtematosus - Altered Expression of TCR Zeta Chain

   [Tsutomu Takeuchi]

   Saitama Medical Center, Saitama Medical School, Japan

2. RAGE: Involvement in the Pathogenesis of Diabetic Complications and Cellular Dysfunction in Amyloidoses

   [David M. Stern]

   College of Physicians and Surgeons of Columbia University, USA

3. Carbonyl Stress and Metabilic and Neurological Diseases

   [Toshio Miyata]

   Tokai University School of Medicine, Japan

4. Intracytoplasmic Inclusions and Mechanisms of Neurodegenerative Disease

   [James E. Galvin]

   Allegheny University of the Health Scinences, USA

5. CAG Repeat Diseases - similarities and dissimilarities with the other 'protein storage disorder's

   [Nobuyuki Nukina]

   RIKEN Brain Science Institute, Japan