第28回 内藤コンファレンス

糖鎖の発現と制御 [I] -機能から病態まで-

組織委員

セッション

Opening Lecture

1. Proteoglycans mediate transport of high molecular weight cargo at the cell surface

   [Jeffrey ESKO]

   Department of Cellular and Molecular Medicine, University of California, San Diego, USA., USA

2. Extensive crosstalk between GlcN acylation and phosphorylation: nutrient/stress regulation of transcription and signaling

   [Gerald HART]

   Department of Biological Chemistry, Johns Hopkins University School of Medicine, USA, USA

SessionA
Development and Regeneration

1. Medical Application of Lectin Microarray: a Powerful Tech-nology for Differential Glycan Profiling

   [Jun HIRABAYASHI]

   Lectin Application and Analysis Team, Research Center for Medical Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST) , Japan, Japan

2. Functions of glycoconjugates in the membrane microdomains in development

   [Koichi HONKE]

   Department of Biochemistry and Kochi System Glycobiology Center, Kochi University Medical School, Japan, Japan

3. Sulfated glycan function in development: from Drosophila to ES cells

   [Shoko NISHIHARA]

   Laboratory of Cell Biology, Department of Bioinformatics, Faculty of Engineering, Soka University, Japan, Japan

4. Role of HNK-1 glyco- epitope in spine morphogenesis

   [Shogo OKA]

   Department of Biological Chemistry, Human Health Sciences, Graduate School of Medicine, Kyoto University, Japan, Japan

5. Kidney failure and early postnatal death in CMP-sialic acid synthetase mutant mice

   [Rita GERARDY-SCHAHN]

   Department of Cellular Chemistry, Hannover Medical School, Germany, Germany

SessionB
Immunoglycobiology and Membrane Receptors

1. Sulfated carbohydrate ligands for selectins and siglecs

   [Reiji KANNAGI]

   Department of Molecular Pathology, Research Institute, Aichi Cancer Center, Japan, Japan

2. Importance of chondroitin sulfate chains during development

   [Hiroshi KITAGAWA]

   Department of Biochemistry, Kobe Pharmaceutical University, Japan, Japan

3. Hydroxylation of glycosphingolipids and membrane functions

   [Akemi SUZUKI]

   Institute of Gycoscience, Tokai University, Japan, Japan

4. Control of infectious diseases by functional modulation of B lymphocyte lectins

   [Takeshi TSUBATA]

   Graduate School of Biomedical Science, Tokyo Medical and Dental University, Japan, Japan

5. Potential for targeting siglecs for treatment of leukemia and autoimmune diseases

   [James PAULSON]

   Department of Chemical Physiology, The Scripps Research Institute, USA, USA

SessionC
Biomarker Discovery

1. Applying glycoproteomics to cancer research: development of potential cancer diagnostics and therapeutics

   [Michael PIERCE]

   UGA Cancer Center and Complex Carbohydrate Research Center, University of Georgia, USA, USA

2. Importance of N-glycan for integrin function

   [Jianguo GU]

   Division of Regulatory Glycobiology, Institute of Molecular Biomembrane and Glycobiology, Tohoku Pharmaceutical University, Japan, Japan

3. Fucosylation and human diseases

   [Eiji MIYOSHI]

   Department of Molecular Biochemistry and Clinical Investigation, Osaka University Graduate School of Medicine, Japan, Japan

4. Glycohepato test: translation to the clinical laboratory setting

   [Nico CALLEWAERT]

   Unit for Molecular Glycobiology, Department for Molecular Biomedical Research, VIB, Belgium, Belgium

5. Development of glyco-biomarkers for liver fibrosis, and liver cancers and others using newly developed technologies for glycomics

   [Hisashi NARIMATSU]

   Research Center for Medical Glycoscience (RCMG), National Institute of Advanced Industrial Science and Technology (AIST), Japan, Japan

SessionD
Glycans in Diseases [ I ]

1. An emerging congenital disorder of glycosylation target: dolichol

   [Hudson H. Freeze]

   Sanford-Burnham Medical Research Institute, La Jolla, CA, USA, USA

2. Co-evolution of NXS/T sites, N-glycan branching and regulation of metabolism

   [James DENNIS]

   Samuel Lunenfeld Research Institute, Department of Molecular Genetics, University of Toronto, Canada, Canada

3. Roles of N-glycan branchings in disease

   [Naoyuki TANIGUCHI]

   Department of Disease Glycomics (Seikagaku Corporation), the Institute of Scientific and Industrial Research (ISIR), Osaka University, Japan
   Systems Glycobiology Research Group, Chemical Biology Department, Advanced Science Institute, RIKEN, Japan, Japan

4. Galactose/calcium-type lectins in inflammation and immunity

   [Tatsuro IRIMURA]

   Laboratory of Cancer Biology and Molecular Immunology, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Japan, Japan

5. Role of sulfatide in influenza A virus infection

   [Takashi SUZUKI]

   Department of Biochemistry, School of Pharmaceutical Sciences, University of Shizuoka, Japan, Japan

SessionE
Glycans in Diseases [ II ]

1. Axonal regeneration and proteoglycans

   [Kenji KADOMATSU]

   Department of Biochemistry, Graduate School of Medicine, Nagoya University, Japan, Japan

2. Protein O-mannosylation and its pathological role

   [Tamao ENDO]

   Molecular Glycobiology, Tokyo Metropolitan Institute of Gerontology, Japan, Japan

3. Investigating the role of LARGE in dystroglycan glycosylation

   [Jane HEWITT]

   Institute of Genetics, School of Biology, University of Nottingham, UK, UK

4. Biosynthesis and deficiencies of GPI-anchored proteins

   [Taroh KINOSHITA]

   Department of Immunoregulation, Research Institute for Microbial Diseases, Osaka University, Japan, Japan

5. Role of O-fucose in signaling and development

   [Robert HALTIWANGER]

   Department of Biochemistry and Cell Biology, Stony Brook University, USA, USA